The Ellison Medical Foundation Colloquium on the Biology of Aging The Ellison Medical Foundation Colloquium on the Biology of Aging will be held at The Buck Institute in Novato, California on October 23-25, 2004. Those who would like to attend should contact Anne Starr, of The Buck Institute, at phone number 415-209-2205.
Information on The Buck Institute can be found at http://www.buckinstitute.org/about.htm
Colloquium on the Biology of Aging
AGENDA
Saturday, October 23
8:10 Introductions
Dale Bredesen, M.D., President & CEO, The Buck Institute
Joshua Lederberg, Ph.D., Chair, Scientific Advisory Board,
The Ellison Medical Foundation
Richard L. Sprott, Ph.D., Executive Director,
The Ellison Medical Foundation
8:30 – 9:05 Steven N. Austad, Ph.D.
University of Texas Health Science Center at San Antonio
Genetic Mechanisms of Exceptional Oxidative Resistance in Birds
9:05 – 9:40 Philip C. Hanawalt, Ph.D.
Stanford University
Repair of Oxidative DNA Damage in Human Neurons
9:40 – 10:15 David Ron, M.D.
The Skirball Institute, New York University School of Medicine
Proteotoxicity and Aging
10:15 – 10:45 Break
10:45 – 11:20 James E. Cleaver, Ph.D.
University of California, San Francisco
Endogenous DNA Damage and Mechanisms of Aging
11:20 – 11:55 James Sherley, M.D., Ph.D.
Massachusetts Institute of Technology
Identification of Chemical “Age Spots” on Immortal DNA Strands in
Adult Stem Cells
11:55 – 1:00 Lunch
1:00 – 1:35 Roger Brent, Ph.D.
Molecular Sciences Institute, Berkeley, CA
Identification of Protein Regulators of Self-renewal, Differentiation, and Senescence in Embryonic Stem Cells
1:35 – 2:10 David Q. –H. Wang, M.D., Ph.D.
Beth Israel Deaconess Medical Center, Harvard Medical School
Aging and Cholesterol Gallstone Formation: Molecular Mechanisms of Gallstone (Lith) Genes
2:10 – 2:45 Huaxi Xu, Ph.D.
Burnham Institute
Gonadal Steroid Regulation of β-Amyloid Generation: Cellular
Mechanisms and Animal Models
2:45 – 3:20 Hui Zheng, Ph.D.
Baylor College of Medicine
An Inducible Gene Knockout System for Alzheimer's Disease and Aging
Research
3:20 – 3:50 Break
3:50 – 4:25 Peter J. Hornsby, Ph.D.
University of Texas Health Science Center at San Antonio
Cell Transplantation Models for Gene Action in Human Aging
4:25 – 5:00 Stewart Frankel, Ph.D.
Yale University School of Medicine
The Regulation of Chromatin and Longevity
Sunday, October 24
8:00 – 8:35 Danesh Moazed, Ph.D.
Harvard Medical School
Connections Between the Nucleolus and Cellular Aging
8:35 – 9:10 Zhou Songyang, Ph.D.
Baylor College of Medicine
Functional Analysis of Aging and Cell Survival Signal Pathways in Mammalian Cells
9:10 – 9:45 Gretchen J. Darlington, Ph.D.
Baylor College of Medicine
Identification of Candidate Genes for Longevity in Long Lived Mouse Models
9:45 – 10:20 Jay M. Edelberg, M.D., Ph.D.
Weill Medical College of Cornell University
Regulation of Senescent Angiogenic Potential
10:20 – 10:50 Break
10:50 – 11:25 Jeffrey S. Friedman, M.D., Ph.D.
The Scripps Research Institute
The Role of p66shc in Cellular Senescence and Mammalian Aging
11:25 – 12:00 Peiqing Sun, Ph.D.
The Scripps Research Institute, La Jolla, CA
A Genetic Approach to Identification of Genes Involved in Cellular Senescence and Immortalization
12:00 – 1:00 Lunch
1:00 – 1:35 Nir Barzilai, M.D.
Albert Einstein College of Medicine
Identification of Longevity Genes in Founder Populations
1:35 – 2:10 Dominique Broccoli, Ph.D.
Fox Chase Cancer Center
Molecular Mechanisms of Telomere Dependent Senescence
2:10 – 2:45 Jack D. Griffith, Ph.D.
University of North Carolina at Chapel Hill
Telomere Looping and Control of Cell Aging
2:45 – 3:15 Break
3:15 – 3:50 Jeff J. Sekelsky, Ph.D.
University of North Carolina
Functional Characterization of a Drosophila RecQ Helicase
3:50 – 4:25 David K. Orren, Ph.D.
University of Kentucky Chandler Medical Center
Understanding the Role of Genomic Instability in Human Aging: The Paradigm of the Premature Aging Disease Werner Syndrome
4:25 – 5:00 Lawrence A. Loeb, Ph.D.
University of Washington
Aging in Mutator and Antimutator Mice
5:00 – 5:35 Weidong Wang, Ph.D.
NIH/NIA-IRP
Characterization of a Novel Protein Complex Involved in the Human Premature Aging Disease—Werner’s Syndrome
Monday, October 25
8:30 – 9:05 Sherman M. Weissman, Ph.D.
Yale University School of Medicine
The Molecular/Physiological Basis for Accelerated Aging in the Werner’s Syndrome
9:05 – 9:40 Bruce N. Ames, Ph.D.
Children’s Hospital Oakland Research Institute
Reversal of Mitochondrial Decay: From Rats to Humans
9:40 – 10:15 David S. Thaler, Ph.D.
The Rockefeller University
Mitochondrial Mutation and Aging
10:15 – 10:45 Break
10:45 – 11:20 Douglas C. Wallace, Ph.D.
University of California, Irvine
Mitochondrial Aging in the Chimpanzee
11:20 – 11:55 Phillip B. Carpenter, Ph.D.
University of Texas Health Science Center at Houston
Biochemical Characterization of a Putative p53-binding
Protein from Xenopus
12:00 Lunch
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