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Nobel Prize Awarded to Linda Buck
Linda B. Buck of the Fred Hutchinson Cancer Research Center will share the
2004 Nobel Prize in Medicine with Richard Axel of the Howard Hughes Medical
Institute. Their independent work on the basic biology of the sense of smell
led to identification of genes responsible for specific odor receptor proteins
and the pathways of olfactory messages between the nose and the brain. The Nobel
Prizes will be presented by His Majesty the King of Sweden in Stockholm, Sweden
on December 10, 2004.
Buck is in her final year as an Ellison Medical Foundation Senior Scholar
in Aging and has been doing research to screen large chemical libraries for
compounds that extend lifespan in C. elegans in order to determine the
identities of the molecules with which they interact in the organism. Using
cutting edge screening tools she is working to identify the multiple processes
that can influence aging as well as those that may operate in a subset of cells
to exert a higher level "central" control over aging throughout the body, and
thus do for longevity genes, what she and Richard Axel did for the biology of
olfaction.
For further information, see http://nobelprize.org/medicine/laureates/2004/index.html.
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